Antimicrobial studies on extracts of Lantana Camara. Linn

[摘要] To study the antimicrobial activity of Lantana Camara. Linn, and its isolated constituent andalso to find phytochemical constituents. The leaves of the plant under study was collected andprocessed for hot extraction by soxhlet apparatus using ethanol and water as solvents. From thequalitative analysis phytochemical evaluation revealed the presence of flavanoids, triterpenoids,alkaloids, and volatile oils. Its antimicrobial sensitivity testing was detected by measuring thezone of inhibition of different bacterial culture using disc plate method. Alcohol extract showedmore antibacterial activity than water extract, against E.coli Bacillus aureus, Pseudomonasauroginosa, and Staphylococcus aureus. Among them these extracts have more antimicrobialactivity towards E.coli. When compared with the standard gentamycin, the extract showedcomparable antimicrobial activities. Phytochemical studies indicates that the presence offlavanoids, volatile oils, triterpenoids, alkaloids, and carbohydrates. Presence of triterpenoidsmay be responsible for the antibacterial activity. Large scale production of active constituents ofLantana Camara. Linn would be an advantageous for natural, herbal antimicrobial agents.

[学科分类] 药理学