Influence of various stressors on the thyroid function and to set upits correlation with the markers of oxidative stress in blood

[摘要] In this set of experiment, the rats were grouped and exposed to physiological, chemical and psychological stressor over a sufficient long period and at the end of the exposure, the levels of thyroid hormones such as T3, T4 and TSH as well as the levels of oxidative stress-markers such as lipid peroxidation (LPO), superoxide dismutase (SOD), catalase (CAT) and reduced glutathione (GSH) were studied only in blood as the oxidative stress in blood may represents the generalized stress in the body. It was postulated that thyroxin may play important role in induction of oxidative stress. Variations of the levels of thyroid hormones can be one of the main physiological modulators of in vivo cellular oxidative stress. The thyroid hormones may play a crucial role in inducing the generation of generalized oxidative stress.

[学科分类] 药理学