Formulation and Characterization of Fast Dissolving Buccal Films: A Review

[摘要] There is always increasing demand for patient convenience and compliance related research and a novel method is the development of fast dissolving buccal films, which dissolve or disintegrate instantly on the patient buccal mucosa. This fast dissolving drug delivery system (FDDS) is suited for the drugs which undergo high first pass metabolism and is used for improving bioavailability with reducing dosing frequency to mouth plasma peak levels, which in turn minimize adverse/side effects and also make it cost effective. In the present review, recent advancements and literature regarding fast dissolving buccal films is compiled and it suggests that this delivery system can be adopted by various pharmaceutical companies in the future at the large scale.

[学科分类] 药理学