A preliminary study on anti-inflammatory activity of Cayratia pedata leaves on wister albino rats

[摘要] The aim of the present study was to evaluate the Anti-inflammatory principle of the Chloform, Alcoholic and Aqueous extract of the leaves of Cayratia pedata Lam. (Vitaceae). The extracts are evaluated for Anti-inflammatory potential using Carrageenan induced paw oedema in albino rats. Diclofenac sodium (20mg/kg) was used as standard positive control. Chloform, Alcoholic and Aqueous extracts are administered at the doses of 200mg/kg and 400mg/kg/body weight. Chloroform and Aqueous extract in 200mg/kg and 400mg/kg doses exhibited significant (P<0.001) and (P<0.01) Anti-inflammatory activity respectively; Whereas Alcoholic extract showed significant activity at 200mg/kg (P<0.001). The present study indicates that Chloroform, Alcoholic and Aqueous extract of the leaves of Cayratia pedata exhibited significant antiinflammatory potential/ properties.

[学科分类] 药理学