Effects of probiotic supplementation on glycemic and lipidemic status in trained body builders

[摘要] With attention to beneficial effects of probiotics on glycemic status and cholesterol level, this study is conducted in order to answer the question of what affect the use of probiotic supplements on glycemic and lipidemic indices in body-builder athletes. Athletes were randomly assigned to two groups taking probiotic and placebo groups, respectively. The procedure has four main steps include: 1-PEPS; pre-exercise and pre-supplementation (onset of experiment), 2- EPS; post-exercise and pre-supplementation (after first time exercise and before supplementation), 3- ES; post-exercise and post-supplementation (after first time exercise and 30day probiotic/ or starch capsule supplementation), 4- ESE; post- supplementation and post-exercise (after 30day probiotic/ or starch capsule supplementation and after second time exercise). Blood samples were taken at each of these four steps. Before probiotic-supplementation, subjects attended the aerobic training. Next, subjects have Bruce test. Probiotics (familac) in capsule was as a combination of several types of probiotics (dosage of 1 capsule per day). Based on obtained result, there is no any considerable difference between groups for insulin and glucose levels before and after probiotic supplementation. The probiotic supplementation and second exercise caused significant decrease in plasma lipids, whereas high density lipoprotein- cholesterol (HDL-C) was not differed between control and supplemented group. In conclusion, probiotic supplementation along with exercise protocol (trained-individual) may have considerable hypolipidemic effect via decreasing total cholesterol and triglyceride, whereas didn’t have considerable effect on glucose and insulin level in trained athletes.

[学科分类] 药理学