In vitro assessment of the efficacy of free-standing silver nanoparticles isolated from Centella asiatica against oxidative stress and its antidiabetic activity

[摘要] The Green synthesis of silver nanoparticles developed into a significant branch of nanotechnology and there is an escalating commercial demand for nanoparticles due to their extensive applications. The present investigation focuses on the green synthesis of silver nanoparticles (CANPs) by utilizing the reducing activity of Centella asiatica and exploring the anti-diabetic property exhibited by CANPs, followed by UV-Visible spectrophotometry, X-Ray Diffraction (XRD) analysis and Scanning Electron Microscope (SEM) for characterization. The shape and size of CANPs were studied using Transmission Electron Microscopy (TEM). UV-Visible spectrophotometry showed the Plasmon resonance peak at 430nm. The antioxidant and antidiabetic property of CANPs was determined. These results indicate that CANPs possess effective anti-oxidant and anti-diabetic properties. In entirety, the silver nanoparticles prepared are safe to be free in the environment and perhaps utilized in industrial and remedial purpose.

[学科分类] 药理学