An Efficient Multicomponent One pot Synthesis of 1, 4-Dihydropyridines withBa(NO3)2 as a Heterogeneous Catalyst Under solvent free conditions

[摘要] Syntheses of 1, 4–dihydropyridines were accomplished by the condensation of Aceto acetnilide with Aldehyde and Ammoniumacetate in the presence of Barium nitrate as catalyst under solvent free condition. An excellent yield (83% to 96%) with less time (10 to 25 minits) at room temperature easy, work up and solvent free reaction is the novelty. These compounds were colorless to pale yellow colored crystalline solids. These compounds structures were elucidated with the help of Spectral studies - IR, 1H NMR, 13 C NMR, Mass and Elemental analysis.

[学科分类] 药理学