Synthesis and antimicrobial activities of new Schiffs base and metal complexes derived from imidazole

[摘要] Schiff base ligand (BCIMED) was synthesized by reacting 2-n-butyl-5-chloroimidazol-4-carbaldehyde and ethylenediamine with metal complexes [Mg(C18H26Cl2N6;]Cl2, [Ni(C18H26Cl2N6;]Cl2, [Zn(C18H26Cl2N6;]Cl2 and [Pb(C18H26Cl2N6;]Cl2 in 2:1 ratio in methanol solution. The Schiff base ligand and their metal complexes have been characterized with the help of elemental analysis, and their structure configuration has been determined by various spectroscopic methods such as IR, 1H NMR, 13C NMR, and Mass techniques etc., Electronic spectra of the complexes indicate that the geometry of the metal center was square pyramidal. These metal complexes were also tested for their antimicrobial activities to assess their inhibiting potential.

[学科分类] 药理学