WWP2: A Multifunctional Ubiquitin Ligase Gene

[摘要] The ubiquitin-proteasome system plays an important role in various celluar processes. WWP2, a recently identified ubiquitin E3 ligase, has been proved a multifunctional gene by degradation a series of targets via ubiquitin-dependent proteasome system, including PETN, Smads, Oct4, EGR2, TIRF and so. Hereafter, we reviewed the recent research process about the function of WWP2.

[学科分类] 生理学与病理学

[关键词] Cancer;