Further Attempts to Transfer the Immunological Response of Tuberculous Animals

[摘要] Three groups of experimental efforts to transfer to other animals the increased immunologic response of tuberculous animals have been described. The transfer of tuberculous omenta or tuberculous peritoneal exudate, a few minutes after the injection of egg-white, to the peritoneal cavity of normal pigs was unsuccessful. Where a similar transfer was made into the peritoneal cavity of a previously infected animal—in a stage of infection in which the injection of egg-white alone does not produce the characteristic effect—irregular positive results were obtained. A simultaneous injection of egg-white and tubercle bacilli was in these guinea pigs often successful.The experiments suggest that two factors are involved, ( a ) the effect which the lesion itself produces upon the antigen, and ( b ) a certain preparation of the organism as a whole occurring during the course of the infection.

[学科分类] 生物科学（综合）