Studies on Hemagglutination Inhibition Phenomena

[摘要] An antigen which interferes specifically with the agglutination of red cells sensitized with Chang's ESS has been demonstrated in the tissues of mice infected with murine typhus.The antigen is heat stable, does not sensitize cells, and does not fix complement.The soluble antigen used in the CF test also interferes with the agglutination of sensitized cells, but has not been demonstrated to be present in mouse or guinea pig tissues.The injection of cortisone increases the amount of interfering antigen, probably by enhancing the multiplication of rickettsia in the infected mice.The possible diagnostic use of this antigen is suggested.

[学科分类] 生物科学（综合）