The Reactions Between Normal Human Red Cells and Antiglobulin (Coombs) Serum

[摘要] It is demonstrated that normal red cells are capable of reacting with antiglobulin (Coombs) serum so as to reduce its power to agglutinate Rh sensitized cells.The reaction is shown to be a specific combination between antiglobulin antibody and a globulin-like antigen on the normal cell surface.This antigen may be modified by the action of trypsin in such a way as to render it non-reactive, but the reactivity of the cell may be restored by treatment with normal human serum.

[学科分类] 生物科学（综合）