New Tissue Culture Systems for Influenza, Newcastle Disease and Vaccinia Viruses

[摘要] Newcastle-disease virus and vaccinia virus were shown to multiply in cultures of HeLa-strain human carcinoma cells, causing cell destruction.Several strains of influenza virus (A and B) multiplied in cultures of chick-embryo lung cells, but only NWS caused cell damage.Both NWS and NDV multiplied in chick-embryo liver cultures and caused cell damage.The period and conditions of culture affected the production of virus and the destruction of cells.Interference between influenza viruses and between influenza and NDV viruses has been shown in chick-embryo cultures by preventing multiplication of, or cell destruction by, the second virus.The mean yield of hemagglutinating WS particles in infected chick-embryo lung cultures was 650 per cell.

[学科分类] 生物科学（综合）