Passive Anaphylaxis in Mice with γG Antibodies
[摘要] Anaphylactic release of histamine from mouse mast cells passively sensitized by purified homologous anti-hapten antibodies was demonstrated. The reaction was critically dependent on the Ag-Ab proportions used for sensitization and challenge and could be provoked by addition of freshly prepared Ag-Ab complexes. No fixation of the antibodies to the cells prior to the Ag-Ab reactions could be demonstrated. The release of histamine was complete 2 min after challenge.
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[效力级别] [学科分类] 生物科学(综合)
[关键词] [时效性]