Rhinoviruses: Basis for a Numbering System

[摘要] In comparative neutralization tests to enumerate serotypes among 68 rhinovirus strains, many one-way heterotypic reactions were encountered. Heterologous serum titers of 64 and above were not uncommon. This heterologous reactivity could be removed from antisera by absorption with human liver powder without altering homologous neutralizing antibody levels. It was concluded that these inhibitors were not specific for rhinoviruses and most likely are antibodies directed against host cell components.Following the removal of nonspecific inhibitors from antisera by absorption with human liver powder, cross-neutralization test results were more readily interpreted. Fifty-five distinct serotypes and one subtype were found among the 68 rhinovirus strains.

[学科分类] 生物科学（综合）