The Effect of Passive Antibody on Protein Synthesis in Lymph Node Cells of Immunized Rats

[摘要] The incorporation of leucine into popliteal lymph node cells was studied in immunized rats some of which received passive antibody 2 days after antigen. In rats receiving antigen alone, there was a phase of increased incorporation into the cytoplasm beginning on day 4, which corresponded to the phase of rapid antibody synthesis. The administration of passive antibody prevented this phase but transiently stimulated increased incorporation of leucine, which reached a peak on day 4. It was suggested that this transient phase represents stimulation of lymphocytes by antigen-antibody complexes.

[学科分类] 生物科学（综合）