Studies of a Myxovirus Isolated from Human Blood

[摘要] 1. 1. Using agar overlaid primate cell cultures, a plaque-forming agent was obtained from human whole blood whereas cytopathic effects were not evident in parallel fluid cultures.2. 2. This agent, termed the DA virus, was classified as a myxovirus and was found to have biologic properties similar to those of the mumps-NDV group.3. 3. Using techniques of neutralization of infectivity either by plaque reduction or by hemadsorption-inhibition the DA virus was found to be antigenically distinct from influenza A, B and C, Newcastle disease, and parainfluenza 1, 2, 3 and 4 viruses. Some degree of antigenic similarity was found to mumps virus. A complete serologic cross-reaction was found between the DA virus and the SA and SV-5 viruses.4. 4. Normal monkeys were found to have antibodies to the DA virus while in captivity.

[学科分类] 生物科学（综合）