Antibodies to Strychnine

[摘要] Antibodies specific for strychnine were obtained from rabbits injected with mono-aminostrychnine-azohemocyanin. Precipitation with caseinazostrychnine was inhibited by the alkaloid and some of its amino, nitro, and methoxyl derivatives, but not by morphine, quinine, etc. , or even by tryptophane, which like strychnine, contains the indol nucleus. The sera were too weak (0.05 mg ab-N/ml) to neutralize the lethal effect of strychnine in mice.A failure to produce antimorphine is recorded.Various aspects of the general topic are discussed.

[学科分类] 生物科学（综合）