A Comparative Study of Antigens for the Gonococcal Complement Fixation Test

[摘要] Of the four methods for producing gonococcal antigen for the complement fixation diagnostic test which have been compared, a “dissolved” antigen prepared by a modified Price method is recommended because of superior sensitivity, immediate availability and stability.In view of our finding that strains of gonococcus vary greatly in anticomplementary property, in the sensitivity and breadth of valence exhibited by their protein fraction, the importance of careful selection of strains employed in the antigen is stressed. A Price-type antigen prepared with two strains selected in reference to the above attributes has given the best results in an extensive series of comparative tests.

[学科分类] 生物科学（综合）