Comparison of Mouse-Protective Tests and Chick-Protective Tests of Over 600 Chemicals Against Pasteurella Multocida

[摘要] Mouse-protective tests and chick-protective tests have been used to determine possible in vivo activity for over 600 chemicals tested for in vitro activity against P. multocida by McKenzie and co-workers (1948). None of the chemicals other than the sulfonamides showed in vivo activity against Pasteurella multocida . The chemicals showing superior activity were 2-sulfanilamidopyrimidine, 2-sulfanilamidopyrazine and their chloro-, bromo-, and methyl derivatives.

[学科分类] 生物科学（综合）