The Action of Urea and Some of Its Derivatives on Bacteria

[摘要] The experiments reported in this paper indicated that hexyl carbamate was able to produce inhibition of growth of several gram-negative and gram-positive bacteria. The concentration of this compound required to suppress bacterial multiplication was found to be less than that necessary with urea, urethane, propyl or isopropyl carbamate, and butyl or isobutyl carbamate. These results emphasize the previously recorded observation that an increase in the number of carbon atoms in the alkyl chain replacing one of the—NH2 groups in urea results in augmentation of antibacterial activity. A concentration of the hexyl compound sufficient to kill bacteria could not be obtained; this was probably due to its relative insolubility.

[学科分类] 生物科学（综合）