Immunologic Studies of Heart Tissue

[摘要] An alcohol-extractable sarcoplasmic antigen previously identified in the hearts of several mammalian species, may be differentiated from cardiolipin by absorption and immunohistochemical tests. Antibody titers to these 2 antigens were found to vary independently in sera of rabbits immunized with homogenates of beef heart or rat heart tissue. Absorption of these sera with cardiolipin did not remove antibody to the sarcoplasmic antigen, while absorption with heart tissue homogenate removed both antibodies. Both antigens are constituents of the myocardial cell sarcoplasm; however, differences in their histochemical properties can be demonstrated.

[学科分类] 生物科学（综合）