Renaissance of Pre-Ehrlich Immunology

[摘要] 1. 1. There is convincing evidence that injected antigens undergo a series of chemical “hybridizations” in animal tissues, and suggestive evidence that the resulting antigen-tissue “hybrids” become semi-permanently “symbiotic” with these tissues, both terms, of course, being used metaphorically.2. 2. Whether or not these “symbiotic hybrids” are to be regarded as partially homologized antigens, as specifically alienated somatic proteins (30), or as antigen-somatic-protein conjugates can not be predicted from present biochemical knowledge.3. 3. There is convincing evidence that some of these antigen-tissue “hybrids” have properties simulating those of specific antibodies, but no proof thus far that they are identical with these antibodies.4. 4. There is, however, no evidence at the present time that there is any other physiological method of specific antibody formation.

[学科分类] 生物科学（综合）