The Reaction of the Human Skin to Normal and Immune Guinea Pig Serum

[摘要] 1. 1. The human skin reacts rather regularly, with the immediate type of reaction, to normal guinea pig serum in a dilution of 1:10, and to a lesser degree to one of 1:50.2. 2. Usually, after this reaction, the skin becomes normal in appearance in two to twenty-four hours.3. 3. When an anti-human serum in a dilution of 1:10 is injected, the immediate reaction is not always greater than that due to the normal serum. But a difference is made more evident by using higher dilutions of the sera, indicating a specific antigen-antibody response.4. 4. A further difference in the reactions is seen in the persistence of that to the immune serum, with induration and inflammation for twenty-four hours.5. 5. The degree of the reaction, with both sera, is only slightly reduced by heating the sera for ten minutes at 50°C.

[学科分类] 生物科学（综合）