Immunological Studies in Active Vaccination against Scarlet Fever

[摘要] The literature before 1930 on active immunization against scarlet fever has been summarized by Thomson and Thomson (1). Rector (2), also, has recently studied statistical data covering about 60,000 individuals inoculated with Dick toxin in which there was an attack rate of 0.5 per cent for the immunized individuals as against 14 per cent for the known susceptibles. Anderson's (3) statement, therefore, appears to be true that “Immunization with Dick toxin in adequate doses confers on a person previously susceptible a level of resistance against clinically recognizable scarlet fever comparable to that shown by a negative test.”Granted then that most investigators agree on this point, considerable disagreement nevertheless exists as to whether active immunization against scarlet fever protects against the erythrogenic toxin only, or whether it also increases resistance to the invasiveness of the streptococcus and to other manifestations of the infection.

[学科分类] 生物科学（综合）