An Ultramicro Technic for Precipitation and Agglutination Reactions

[摘要] The capillary tube technic developed by Richards, Bordley and Walker for the ultramicro chemical analysis of minute amounts of fluid has been adapted for the performance of certain immunological reactions. Precipitation and agglutination tests have been made with as little as 0.1 cu.mm. of reacting material. The sensitivity and reliability were found to be equal to those of standard macro methods. The apparatus required is neither expensive nor difficult to obtain and the technic is easily mastered.The obvious advantages of the ultramicro method are the minuteness of the quantity of fluid required and the rapidity with which a determination can be completed. An additional advantage is the opportunity for microscopic observation of the precipitation and agglutination during the course of the reaction. The vividness with which the reactions may be seen contributes an appreciation of the character of these phenomena even to an observer experienced with macro methods.

[学科分类] 生物科学（综合）