Merthiolate Versus Phenol As a Preservative for Diphtheria Toxoids—Diluted and Undiluted at Icebox and Room Temperatures

[摘要] 1. 1. Undiluted or diluted diphtheria toxoids, when kept at icebox temperature and tested after 5 months did not show any difference in their antigenic or flocculating value whether preserved with merthiolate 1:10,000 or phenol 0.5 per cent.2. 2. When kept at room temperature for 5 months, the phenol preserved toxoid diluted 1:2 though preserving its flocculating value shows deterioration in its antigenic value.3. 3. Undiluted toxoids preserved with phenol and kept at icebox temperature for 9 and 18.5 months do not compare favorably in their antigenic value with the merthiolated toxoid diluted 1:3 and kept in the icebox over 2 years.4. 4. Merthiolated toxoid diluted 1:3 and kept at icebox temperature preserves its antigenic value better than the merthiolated toxoid diluted only 1:2 but kept at room temperature.[1][1] [1]: #fn-1

[学科分类] 生物科学（综合）