An Allergic Reaction of the Tuberculous Uterine Horn

[摘要] The reactivity of the uterus of the sensitized guinea-pig in the anaphylactic experiment has received much study and has contributed greatly to the understanding of the mechanism of specific allergic phenomena. The experiments recorded here are simply an application of the principle of specific reactivity between antigen and its homologous antibody, employing the sensitive uterus as an indicator.Immediately after the publication by Weil (1) in 1917 of his results upon the reaction of the tuberculous guinea-pig uterus to Old Tuberculin, experiments were started with the idea of using this method to detect tubercle protein or specific products of tubercular metabolism in the urine of cases of tuberculosis. Such experiments were based in part upon the results of Blake (2) in reporting specific precipitinogen in the urine in pneumonia, and in part upon the intimate relationship which had been shown to exist between precipitin and anaphylactic antibody by Weil and others.

[学科分类] 生物科学（综合）