The Action of Various Metallic Salts on Hemolysis

[摘要] What has been examined in this study is the significance of the presence of small quantities of metallic salts on the hemolytic action of saponin on horses' blood-corpuscles, of staphylolysin on goats' blood-corpuscles, and of complement-amboceptor on sheep blood-corpuscles. By determining the minimal dose of the individual salts (in molecular solution) at which their action is demonstrable, it is possible to obtain a comparison between the action of the different salts. While some salts exert an inciting action on hemolysis, others exert an inhibitive one (positive and negative catalysis?); some show an inciting effect at one concentration and an inhibiting one at another (table 5).On examining blood-corpuscles to which is bound as large a quantity of a metallic salt as can be bound thereto without acting perceptibly destructively, the stability of such blood-corpuscles towards the action of hemolytic substances will be found to vary greatly, to which fact the considerable experimental inconstancy in the experiments described should probably be assigned.The anion in the salts seems to be without significance as regards their action in either favoring or inhibiting hemolysis.

[学科分类] 生物科学（综合）