The Relationship of Lipoids and Proteins to Serum Reactions in Tuberculosis

[摘要] While working with sera of tuberculous patients it became necessary to note the effect of ( a ) the removal of lipoids and ( b ) the precipitation of globulins on certain serum reactions. The results obtained seemed sufficiently clear cut for publication in the present paper.Part A. Lipoids in Tuberculo Serum Reactions The relationship of lipoids to immunity reactions has been a subject of great interest in recent years. Krumwiede and NOble (1) have recently been unable to confirm the claim made by Stuber that agglutinins are lipoidal in nature. Levaditi and Yamanouchi (2) have claimed that the substances in syphilitic sera responsible for the Wassermann reaction, can be extracted with alcohol. Noguchi (3) was unable to confirm this observation; he concluded that the reacting substance in syphilitic serum was non-lipoidal in character. Kolmer and Pearce (4) found that ether and chloroform narcosis tended to diminish the concentration of non-specific fixation bodies in normal, inactivated dog and rabbit serum.

[学科分类] 生物科学（综合）