Toxin Production and Virulence of Inaba and Ogawa Vibrios

[摘要] 1. 1. Rabbits receiving the same number of Vibrio cholerae organisms intravenously showed a mortality of 65.5% when injected with the Ogawa subtype, and 15% on injection with the Inaba subtype.2. 2. With lower doses of Ogawa than of Inaba vibrios, 50% mortality in mice was obtained.3. 3. Shredding of the intestinal mucosa of the guinea pig was more marked after the application of Ogawa than of Inaba filtrates.4. 4. Tryptophane enhanced the production of toxic filtrates.5. 5. Cholera filtrates prepared from 16-hr-old cultures had a higher toxicity than those from growth incubated for 10 days.6. 6. The toxic component in cholera filtrates can be preserved for months at -10°C.

[学科分类] 生物科学（综合）