Studies with Measles Virus

[摘要] The isolation and propagation of the agents recovered from patients with measles were carried out in 3 different tissue culture systems: human amniotic membrane, human kidney, and monkey kidney cultures.Human amniotic membrane tissue was found as suitable for isolation and propagation of measles virus as was human kidney tissue. Monkey kidney tissue was useful; the difficulties involved in using kidney tissue from monkeys are stressed, since it has been shown that monkey kidney cultures occasionally harbor a virus indistinguishable from measles virus and also frequently contain the “foamy agent.”Details of cytopathogenic changes associated with measles virus are described for cultures of human amniotic membrane.

[学科分类] 生物科学（综合）