Studies of Antibodies Against Organ-Antigens

[摘要] Antimouse spleen serum exerted a pronounced effect upon mice as evidenced by ruffled fur, apathy and splenomegaly with histologic changes in the spleen elements. The antiserum did not, however, significantly affect the uptake from the circulation of the colloidal carbon by the RES of the mouse. Substitution of CrP32O4 for the carbon revealed that the spleens of the mice treated with AMSS contained at least twice as much radioactive colloid as spleens of the control mice. The increased uptake might be due to either the preferential stimulation of the spleen RES by the AMSS or by the spleen hyperplasia or by both.

[学科分类] 生物科学（综合）