Evaluation of Electronic Measurements of Hemagglutination for Quantitative Studies

[摘要] The results of an extensive study of the use of total particle measurements obtained by an electronic cell counter for quantitative hemagglutination purposes are presented. Total particle data were shown to yield nonlinear log probit and logit log assay curves. The free cell to total particle relationship was shown to differ with the avidity of the serum and the strength of the antigen on the red cell within a system, and with the pattern of aggregation among blood group systems. It is therefore doubtful that total particle measurements have any useful application in quantitative hemagglutination assay systems.

[学科分类] 生物科学（综合）