Action of the First Component of Complement

[摘要] The interaction of SAC′4 with guinea pig or human C′1 as they exist in whole serum yields an intermediate designated SAC′1,4. This intermediate is activated to SAC′1a,4 even in the absence of fluid phase serum factors at a rate which is dependent on temperature.Partially purified guinea pig C′1 was found to be in the activated state (C′1a) while partially purified human C′1 was found to be in the precursor form.

[学科分类] 生物科学（综合）