Blood Group Antigens and Cross-Reacting Antibodies in Primates, Including Man

[摘要] Orangutan red cells were typed for M blood factors with aid of cross-reacting anti-M reagents prepared from three different kinds of rabbit antisera, namely, against human type M red cells, against chimpanzee red cells, and against baboon red cells. The antisera had been rendered type-specific for human M red cells by absorption with human type N cells. Selective specificity for orangutan red cells was obtained by further absorptions with selected orangutan red cells. In this way, it was found that, among 24 orangutans, 12 were M positive and 12 were M negative. Absorption experiments indicate that human M cells probably have M factors lacking in orangutan M cells, whereas, conversely, orangutan M red cells probably have M factors lacking in human M cells. Although half of the orangutans tested lack M factors, none proved to have the NV factor. Thus, the M-N types of orangutans are not entirely comparable with the M-N types of man, just as had previously been found to be the case for chimpanzees. A suitable terminology to indicate these facts has been proposed.

[学科分类] 生物科学（综合）