Segregation of an Avirulent Variant of Rinderpest Virus by the Terminal Dilution Technique in Tissue Culture

[摘要] 1. 1. Passage of a previously modified strain of rinderpest virus by the terminal dilution technique resulted in segregation of an avirulent virus population.2. 2. Inoculation of cattle with this virus stimulated the development of a significant degree of immunity which protected them against infection with massive doses of virulent virus, without causing a febrile response or lesions.3. 3. The avirulent virus was not spread from inoculated cattle to normal ones by contact.

[学科分类] 生物科学（综合）