The Nonspecific Nature of the Carbohydrate Portion of Horse Pseudoglobulin

[摘要] When recrystallized preparations of pepsin, trypsin, and chymotrypsin are allowed to act on horse pseudoglobulin, the loss of specificity of the protein closely parallels destruction of protein both being completely effected by pepsin.The polysaccharide present to the extent of 3.7 per cent in horse globulin, whether prepared by the method of Rimington, using baryta, or by a method which would preserve any acetyl groups originally present, gives neither specific precipitative nor inhibitive reactions with homologous antiserum.It is concluded that the polysaccharide of horse globulin has no specificity in the sense that the pneumoccoccal polysaccharides have, the specificity of the globulin being a property of the molecule as a whole.

[学科分类] 生物科学（综合）