The Incidence of Agglutinins for the Paradysentery Bacilli in Serums from Human Beings and from Animals

[摘要] Of 115 normal human serums tested for agglutination with antigens prepared from smooth cultures of three different strains of S. paradysenteriae, positive reactions for the Flexner strain were obtained in 87, 83 and 42 per cent respectively in a dilution of 1:20, and in 49, 43 and 13 per cent at a dilution of 1:80. No significant difference was found in the incidence of agglutinins in serums from males and females. Eight specimens of cord blood showed approximately the same percentages. Of 44 serums tested with one strain of S. dysenteriae, 10 agglutinated in 1:10, 2 in 1:20, none in higher dilutions.Of 120 human serums tested with three strains of S. paradysenteriae, Sonne, 1.6 per cent agglutinated at least one strain in a dilution of 1:20; none in higher dilutions. The same three strains were agglutinated by 100 per cent of beef serums, 96.2 per cent of sheep serums, 93.5 per cent of swine serums, 46.4 per cent of rabbit serums and 22.3 per cent of guinea pig serums. Beef, swine and sheep serum titers were generally high; those for rabbit and guinea pig serums low. Absorption experiments indicated that normal agglutinins for the Sonne organism are not absolutely species-specific.

[学科分类] 生物科学（综合）