Experiments with Staphylococcal Enterotoxin

[摘要] Staphylococcal enterotoxin may be detected by the intra-abdominal injection into kittens of filtrates whose α- and β-toxins have been destroyed by heat or formalinization, or have been removed by preliminary absorption with serum containing antibodies to the α- and β-toxins but not to the enterotoxin.The enterotoxin has definite and specific antigenic properties. The sera of animals immunized with filtrates containing enterotoxin develop neutralizing properties against this antigen.A specific flocculation reaction, apparently involving the enterotoxin and its antibody, is described. Methods are given whereby the flocculation zone, representing the optimal ratios for neutralization of the enterotoxin in a filtrate by its corresponding antibody, may be distinguished from other flocculation zones due to α- and β-toxin-antitoxin reactions.

[学科分类] 生物科学（综合）