Antibody Production in Rabbits Following Injection with Pancreatic Ferments

[摘要] Accumulated investigations give evidence that ferments when injected into suitable animals display antigenic properties in that they stimulate the production of specific antibodies. Thus:Hildebrandt (1) in 1893, produced specific antibodies to the enzyme emulsin. Morgenroth (2) in 1899 and Briot (3) in 1900, were both successful in producing a specific antibody to rennin. In 1901 Achalme (4) produced certain specific antibodies to pancreatin, while Sachs (5) a year later produced similar antibodies to pepsin. In 1903 Levene and Stooky (6) increased the antitryptic action of serum by the experimental injection of pancrease extract, and Halpern (7) in 1911 claimed similar results from the injection of dog pancreas into dogs. Most recently (1914) Marras (8) obtained precipitating and complement-fixing antibodies to trypsin.In the course of experiments directed toward further determination of the antibodies produced to pancreatic ferments, I have made observations that possess a bearing upon the production of antibodies in general and which it is the purpose of this paper to present.

[学科分类] 生物科学（综合）