The Transition Forms of Blood Groups

[摘要] 1. 1. The O antigen is met with in most A and B blood cells and appears independently of their heterozygoty. It manifests itself in different degrees in various groups; that is to say O τ; A2 τ; B τ; A.2. 2. The O-residues may be explained by an incomplete mutation of the O gene in the direction of A and B or vice versa. This O-remnant inhibits the anti-O formation. And so the inagglutinability of the group O by isosera can be explained as the result of an incomplete mutation of the O, A, B genes. A general law reflecting the serological consequence of mutation may be: The isoantibodies against the primary factor are absent when the mutations are incomplete .3. 3. The blood corpuscles A or B of equal contents of the residual O belong according to the author to one pleiade, an idea which can replace the notion of subgroups. By means of appropriate methods further subgroups (pleiades) have been found. It is proposed to term them A5, A4, A3, A2, Am, Ar, Aj, Ac and B2, Bm, Br, Bj, etc. In such a way an international understanding of the subgroups seems to be possible.4. 4. The observations indicate as a general law that the more advanced forms dominate the less advanced, containing more of the residual O . This can be applied not only for subgroups within A and B, but it embraces also the genetic conditions between A and B. It may be that this can have a practical importance in the cases requiring exclusion of paternity.

[学科分类] 生物科学（综合）