The Antigenic Specificity of Syphilitic Antibody Globulin

[摘要] 1. 1. Washed Wadsworth-Brown floccules, presumably consisting of lipoid antigens in combination with syphilitic antibody, evoke in rabbits two different antibodies, one against the lipoid antigen, the other against syphilitic antibody.2. 2. Rabbit anti-syphilitic-antibody reacts equally well, and with high dilutions, with both normal and syphilitic human serum.3. 3. It reacts with the total globulin fraction of normal serum to the same titer as with whole serum, and with water-insoluble globulin to an only slightly lower titer. The water-soluble globulin gives reaction only in 8 to 10 times higher concentration, and the albumin in 1000 times higher concentration.4. 4. The specificity of syphilitic antibody seems to be the same as that of certain normal serum globulins. It seems to be more closely related to the euglobulin fraction than to the pseudoglobulin.

[学科分类] 生物科学（综合）