The Effect Produced in Vitro by Vitamin C on the Toxic and Antigenic Properties of Diphtherial Toxin

[摘要] Diphtherial toxin under limited conditions at pH values which are noninjurious, is inactivated by vitamin C. Evidence supports the view that oxidation of the toxic molecule occurs. Furthermore, toxin-vitamin mixtures are unsatisfactory immunizing agents inasmuch as loss of toxicity is accompanied by a corresponding loss of antigenic properties.

[学科分类] 生物科学（综合）