On the Group-Specific Differentiation of the Human Feces with Special Regard to the AB Group

[摘要] 1. 1. The results of previous investigations of Hodyo and Moharram that normal stools of adults contain group-specific agglutinogens, were confirmed by serologic examinations of the “alcohol-soluble” and “water-soluble fractions” from feces of persons of group: A, B, and O.2. 2. Extracts from AB-feces were also examined. The alcoholic extracts showed a distinct inhibitory effect on the “A-specific sheep hemolysis,” the watery extracts were less effective. The iso-agglutinins (α and β) were inhibited by the water-soluble fraction only.3. 3. No remarkable difference was found between feces from “eliminators” and “non-eliminators.” Both types contain group-specific agglutinogens in their feces. This is true for the AB-group also.4. 4. Concerning the subgroups (A1 and A2, A1B and A2B), the fractions in question from A2- and A2B-feces respectively, reacted generally somewhat more weakly upon the α-agglutinins and heterogenetic sheep hemolysins than the corresponding fractions, containing A1-substance.5. 5. One gram of fresh feces of A-group contains on an average 50 alcohol-soluble group-specific units and 5 water-soluble units. One gram of dried feces (Hodyo-Moharram's method) contains on an average 1000 alcohol-soluble group-specific units and 100 water-soluble units. One group-specific unit represents the smallest amount which still completely inhibits one hemolytic units of an A-specific sheep hemolytic immune serum; 0.02 gram of fresh stool is the smallest amount, necessary for a sure detection of group-specific agglutinogens.

[学科分类] 生物科学（综合）