The Rôle of the Autonomic Nervous System in the Anaphylactic Smooth Muscle Contraction

[摘要] It is generally believed that there is some relationship between the nervous system and anaphylaxis, although opinion on this point is not unanimous. Biedl and Kraus (1) believed that such a relationship does not exist. They based their conclusions on the fact that the low blood pressure in the dog during anaphylactic shock is not raised by the stimulation of the peripheral end of the cut splanchnic nerve, or by the administration of 0.1 to 0.2 mgm. of adrenin, although barium chloride which acts directly on smooth muscle does increase the blood pressure. The fact that adrenin as well acts directly on the smooth muscle was not generally recognized at the time this work was done. Arnold and Leschke (2) conclude that excitation of the parasympathetic fibers is responsible for shock. Pottinger (3) believes vagal stimulation to be a factor, although Scheurer and Strasman have shown that section of the vagi will not prevent shock; they conclude that the nerve endings are responsible if nervous tissue is involved at all.

[学科分类] 生物科学（综合）