A Non-Pathogenic Bartonella-Like Organism Developing in Embryonate Eggs after Injection with Haemobartonella Muris

[摘要] An organism morphologically indistinguishable from Haemobartonella muris and H. tyzzeri has been cultivated in embryonate eggs after inoculation with rat blood infected with H. muris . Subculture on complex cell-free media was obtained, but primary isolation on these media could not be achieved.The organism is an intracellular parasite forming compact spherical cytoplasmic clusters which are identical with those produced by Bartonella bacilliformis and H. tyzzeri and are believed to be almost specific for organisms of this group. Further characteristics supporting the view that the organism is H. muris are growth in fused clumps in cell-free media and inability to ferment carbohydrates.Injection into splenectomized bartonella-free rats resulted in no clinical or hematological evidence of haemobartonellosis and gave no immunity to subsequent infection with H. muris . For this reason, positive identification of the organism cannot be made at present.

[学科分类] 生物科学（综合）