Synthesis, Assembly, and Secretion of γ Globulin by Mouse Myeloma Cells

[摘要] The synthesis and assembly of mouse IgA has been examined in the Adj-PC 6A cell line and in the MOPC 209B and MOPC 315 tumors. The pathway of assembly of the IgA monomer in these tumors appears to be H + H → H2; H2 + L + L → H2L2; H2L2 + H2L2 → (H2L2)n. Final assembly of the monomers of 6A and 315 into IgA polymers occurs close to the time of secretion.

[学科分类] 生物科学（综合）