Recommendations for the Nomenclature of Human Immunoglobulins

[摘要] Terminology for immunoglobulin molecules . Following a proposal made in 1964,[2][1] two symbols (Ig and γ) have been used interchangeably to designate human or animal immunoglobulins. Although it was pointed out that Ig is a logical symbol for immunoglobulins, the symbol was retained as an acceptable substitute, mainly in view of the tradition that had long associated it with the immunoglobulins.In recent years there has been a trend among editors and authors to give increasing preference to the symbol Ig. A major reason for dissatisfaction with the existing dual terminology, Ig and γ, is that the symbol γ is also employed to designate the heavy polypeptide chains of a particular class of immunoglobulins.It is therefore proposed to discontinue the use of the symbol γ for the term immunoglobulin and to apply γ to designate exclusively the heavy chains of immunoglobulin G (IgG). Symbols such as γGl, γD, etc., should be replaced by IgGl, IgD, etc. [1]: #fn-2

[学科分类] 生物科学（综合）