Bacterial Anaphylaxis

[摘要] In 1900 Lustig and Galeotte (1) apparently demonstrated that clinical anaphylaxis could be produced in experimental animals using bacterial proteins. They worked with nucleo-proteins from B. pestis and Microspira comma prepared by the Wooldridge method and the use of strong KOH to dissolve the cell membranes. Their results were confirmed by many workers among whom were, Del Conte, Heller, DeBonis, Tiberti, Savagnone. The European work up to 1913 is well summarized by Lustig (1). In America Rosenau and Anderson (2) were pioneers in the field of bacterial anaphylaxis.Two sources of error have entered into much of the work reported, namely, methods of preparation of protein which racemized (3) it and the use of the intravenous method of demonstration which has caused to be included anaphylactoid (4) as well as true anaphylactic reactions.

[学科分类] 生物科学（综合）